The book presents details on the aliphatic foldamers', with a special emphasis on the peptides with homogeneous backbones (a- and a-peptides), peptides with heterogeneous backbones (from alternating a-, a-, a-, a- and a-amino acids), peptides with backbone modifications (aminoxy-, hydrazine- and ureido peptides), peptides from sugar amino acids and methods for conformational analysis. The material presented in the book is useful for the research and student community to usher in a sustained propagation of this active area of research on foldamers'.