The book's major focus is on quantitative methods of determination of such kinetic mechanisms and binding models that allow the experimentalist to extract interaction and structural parameters to help characterize the biological complexes at hand. All relationships used in such analyses are derived and their physical and mathematical bases discussed. In addition, the models described in this volume are numerically examined and illustrated using relevant examples from the literature. The book should provide the reader with not only a clear indication of how to derive, but also how to use the obtained relationships.