This manual presents comprehensive information on the preparation and feeding of milk replacers and starter feeds for pre-ruminants. Although the substitutes for dam's milk can be prepared from by-products of milk and feed ingredients that are not preferred for human consumption, awareness about such alternatives is limited in many developing countries. Therefore, popularization of preparation and feeding of milk replacers and starter feeds using locally available ingredients is useful in promoting survivability and growth of young stock. The target audiences for this manual are livestock extension workers engaged in developing countries. The manual is also useful for students and teachers of ruminant production and for small scale industries and researchers that wish to produce milk replacers and starter feeds.