Now completely revised and updated, this ground-breaking text focuses on the borderland between histology and pathology. Presented by leading international specialists in pathology, histopathology, anatomical pathology, surgical pathology, and neuropathology, the text is innovative, well organized and generously illustrated. Coverage includes the structure, composition, and function of tissues from a pathologic perspective; a systematic review of each of the major organ systems, as well as structures of special significance; and histologic subtleties, such as unusual variations in staining reactions, little-known fixation artifacts, and frequently missed gross observations. The new edition features brand-new chapters -- including one on apoptosis!