The IFIP International Conference on Network and Parallel Computing is an international conference, aimed at providing an exciting platform and forum for researchers and developers from academia and industry to present their latest research in the ?eld of parallel computing systems and applications. This year NPC received 89 submissions from authors in 11 countries. The papers were reviewed by a 51-member Program Committee, with 26 members from USA, 9 from mainland China, and the rest from Canada, Hong Kong, Taiwan,Korea,Japan,UK,andFrance.Eachpaperreceivedthreetosixreviews. Basedona totalof 287reviews,the ProgramCo-chairsaccepted papersinto two categories: Select papers: 23 papers passed the most stringent selection. Each paper is up to 15 pages in the conference proceedings. The acceptance rate for select papers is 25.8%. Regular papers: 11 additional papers are of su?cient publishable quality. Each paperisupto10pages. For the main conference, we invited three distinguished speakers: - XiaodongZhang(OhioStateUniversity,USA):BuildingaDomain-Knowledge Guided System Software Environment to Achieve High Performance of MulticoreProcessors - HuaiminWang(NationalUniversityofDefenseTechnology,China):Internet- Based Virtual Computing Environment - Jesse Fang (Intel Labs, China) One workshop was held in conjunction with the NPC 2010 conference: the International Workshop on Network on Chip (IWNoC 2010). The workshop was chairedbyHuaxiGuandJiangXu.Theproceedingsoftheworkshopareincluded in this volume.