This issue of Dermatologic Clinics, guest edited by Drs. Divya Srivastava and Rajiv Nijhawan of UT Southwestern Medical Center, is devoted to Cutaneous Oncology and Dermatologic Surgery. Articles in this important issue include: Squamous cell carcinoma: updates on staging and management; AFX/UPS: updates on classification and management; EMPD: updates on management; Merkel Cell Carcinoma: updates on staging and management; The management of skin cancer in the elderly; Topical and systemic modalities for chemoprevention; Medications that increase risk for skin cancer development; Dermatologic surgery in the pregnant or lactating patient; Optimizing patient safety in dermatologic surgery; Perioperative antibiotic use in dermatologic surgery; Post-operative pain management in dermatologic surgery; Novel skin substitutes and surgical dressings; Optimizing the patient experience and patient satisfaction in dermatologic surgery; Surgical and Non-invasive Modalities for Scar Revision; and Pearls for dermatologic surgery in pediatric patients.