The idea for this conference came from a meeting of the IFIP (International Federation for Information Processing) Technical Committee for Information Systems (TC8) in Guimares, Portugal in June 2005. Our goal is to build an IFIP forum among the different Information Systems Communities of TC8 dealing with the increasing important area of Enterprise Information Systems. In this particular meeting the committee members intensively discussed the innovative and unique characteristics of Enterprise Information Systems as scientific sub-discipline. Hence, in this meeting it was decided by the TC8 members that the IFIP TC8 First International Conference on Research and Practical Issues of Enterprise Information Systems (CONFENIS 2006) would be held in April 2006 in Vienna, Austria. Dr. Li Xu (USA) and Dr. A Min Tjoa (IFIP TC8) were assigned to propose a concept for this conference in order to establish an IFIP platform for EIS researchers and practitioners in the field to share experience, and discussing opportunities and challenges. We are very pleased therefore to have this conference organised by the help of the Austrian Computer Society (OCG). OCG supports the idea of this conference due to the urgent need of research and dissemination of new techniques in this key area. We received 180 papers from more than 30 countries for CONFENIS and the Program Committee eventually selected xx papers or extended abstracts, making an acceptance rate of xx% of submitted papers. Each paper was thoroughly reviewed by at least two qualified reviewers.