Bucharest, Romania, 1875:
Dr. Lysander Heistad, a young physician known for his aptitude and unwavering compassion, had always put the needs of others before his own. So when he heard the last request of his beloved little sister who lay dying from Typhoid fever, he never intended to fail in fulfi lling it. However, he had also not forseen himself becoming the target of a horrifying monster out for blood.

New York, New York, 1995:
For more than a century Lysander Heistad's only companions have been other vampires who shun him for his refusal to drink human blood. Consumed by guilt over the death of his sister so long ago, he had believed himself doomed to an eternity of loneliness and regret. When he meets Anna Harper, a beautiful, lonely, fearless mortal who trusts him implicitly, he can hardly believe his good fortune. But as their newfound friendship grows, so grows his struggle to keep her safe, from not only other vampires, but himself as well.