In an effort to capitalize on some of the more positive aspects of peer influences, colleges and universities have created a wide range of peer-to-peer education, leadership, and mentoring roles—especially in the first college year. Yet, the use of peers in first-year seminar instruction is still far from commonplace. Latino and Ashcraft offer guidance on defining the role of peers as co-instructors; recruiting, selecting, and training peer educators; facilitating relationship building within the instructional team; and assessing the impact of peer leaders on the course, the students served, and the peers themselves. Sample training agendas and activities, course syllabi, and evaluations are included.