Michael R. Duchen | Akateeminen Kirjakauppa

This second edition brings together up-to-date contributions
from leaders in the field internationally on the various ways in which
mitochondrial dysfunction contributes to the pathogenesis of neurodegenerative
diseases, including Parkinson’s disease, Alzheimer’s disease and multiple
sclerosis. The reader is guided through the basic functions of mitochondria and
the mechanisms that lead to their dysfunction, and on to the consequences of
this dysfunction for neuronal function before finishing with the modelling of
these disorders and discussion of new potential therapeutic targets. 

Additional chapters have been added to the book to reflect
advances in the field and there are many new contributors and topics, including
how mitochondria are degraded and the interaction of the mitochondria with
pathologically relevant proteins. 











Mitochondrial Dysfunction in Neurodegenerative Disorders
provides an accessible, authoritative guide to this important area for
neurologists; research and clinical neuroscientists; neuropathologists; and
residents with an interest in clinical research.