The 6th edition of a well-known and much used standard text in the field. This book covers all aspects of the biochemical abnormalities caused by various diseases and how they relate to the biochemical changes in the blood, urine, cerebrospinal fluid, joint fluids, other body fluids and in cells. The purpose is to provide the fundamental bases for understanding the biochemical changes that occur in disease processes and in turn to provide the rationale for applying this understanding to the diagnosis of the disease process. A substantial appendix is provided so that the user can quickly identify the reference ranges for a large number of animal species.