Aimed at advanced students as well as professionals and researchers, this advanced textbook provides a comprehensive overview of the current state of knowledge in the field of cellular aging.
Starting out from the definition and description of an aged phenotype of selected tissues, the internationally recognized specialist authors discuss in detail the major molecular players in the aging process. These include both causative agents as well as regulatory circuits and signaling cascades known to affect senescence and their modulation by exogenous and endogenous factors. The text then goes on to introduce biomarkers of aging and laboratory models for the investigation of aging processes. Finally, potential anti-aging approaches are extensively discussed.
Special features such as summary boxes and take-home messages in each chapter enhance the didactic value of this resource, while artwork is available to lecturers for download.
