Medical textbooks are mainly oriented by body systems, disease or diagnosis, yet practicing physicians are confronted with patients’ complaints in the form of symptoms, physical signs or laboratory abnormalities, from which they are expected to reach a diagnosis and proceed with treatment. This book is meant as a pragmatic text for use at the patient’s bedside. It classifies common clinical symptoms and signs, laboratory abnormalities and issues of management as they present themselves in daily practice. Special emphasis is given to new knowledge that has accumulated on the molecular pathophysiology and molecular genetics of various kidney diseases in order to deepen and strengthen the practical approach to common problems in pediatric nephrology. Aimed at an audience of general and family practitioners, pediatricians and trainees who are not exposed on a day-to-day basis to pediatric nephrology problems, it provides a logical, concise and cost-effective approach from which they can profit and acquire medical reasoning.