This book approaches the generic theme of the series – studies in otherness and communication –from the perspectives of urban culture and posthumanist studies. It brings together a broad variety of essays examining the different ways in which agency reinvents itself, whether in the urban space, through the multiple forms and devices of art and culture, or through the relationship with technology and the surrounding environment, as a result of the contemporary conditions of post-humanism and the anthropocene. The sense of becoming other is added through a new paradigm that combines 1) a theoretical-essayistic mode, supported by illustrative cases with 2) the description of artistic processes and literary production. The essays are written by an international group of humanities and social sciences scholars/artists, consisting of Cristina Álvares, Pier Luca Marzo, Edwige Armand, Chiara Mengozzi, Ricardo G. Soeiro, Panagiotis Ferentinos, Mónica Aubán Borrell, Luis Campos Medina, Bill Psarras, Cíntia Sanmartin Fernandes, Micael Herschmann, Mitja Velikonja, Teresa Mora and Tiago Porteiro.