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Gustavo Stolovitzky | Akateeminen Kirjakauppa

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Reverse Engineering Biological Networks - Opportunities and Challenges in Computational Methods for Pathway Inference, Volume 11
Gustavo Stolovitzky; Andrea Califano
John Wiley and Sons Ltd (2007)
Pehmeäkantinen kirja
125,80
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The Challenges of Systems Biology - Community Efforts to Harness Biological Complexity, Volume 1158
Gustavo Stolovitzky; Pascal Kahlem; Andrea Califano
John Wiley and Sons Ltd (2009)
Pehmeäkantinen kirja
122,10
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Reverse Engineering Biological Networks - Opportunities and Challenges in Computational Methods for Pathway Inference, Volume 11
125,80 €
John Wiley and Sons Ltd
Sivumäärä: 452 sivua
Asu: Pehmeäkantinen kirja
Julkaisuvuosi: 2007, 18.12.2007 (lisätietoa)
Kieli: Englanti
Computational biologists are striving to "reverse engineer" the underlying networks of interactions between the molecules in the cell. This volume and the conference it reports on attempt a systematic evaluation of reverse engineering methods. The DREAM project brings together a diverse group of researchers to clarify potentials and limitations of the enterprise of reverse engineering cellular networks. An important aspiration of the project is to compare the effectiveness of different methods in reverse engineering biological networks. Evaluating this requires a "gold standard" network for which at least the true topology of connections is known. Many participants, especially the computational biologists, believe that synthetic networks are good candidates for this purpose because, at least for now, only they can be described with certainty. Experimental biologists, however, worry that unless the project addresses real biological networks, it could evolve into a mathematical exercise with little impact on biology. These and other ideas are discussed.
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Reverse Engineering Biological Networks - Opportunities and Challenges in Computational Methods for Pathway Inference, Volume 11zoom
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ISBN:
9781573316897
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