Tekijä: George C. Tsokos; Larry W. Moreland; Gary M. Kammer; Jean-Pierre Pelletier; Johanne Martel-Pelletier Kustantaja: Humana Press Inc. (2001) Saatavuus: Noin 17-20 arkipäivää
Tekijä: George C. Tsokos; Larry W. Moreland; Gary M. Kammer; Jean-Pierre Pelletier; Johanne Martel-Pelletier Kustantaja: Humana Press Inc. (2012) Saatavuus: Noin 17-20 arkipäivää
Humana Press Inc. Sivumäärä: 709 sivua Asu: Kovakantinen kirja Painos: 1999 Julkaisuvuosi: 1999, 04.05.1999 (lisätietoa) Kieli: Englanti
Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages/monocytes, and endothelial cells. Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.