Nucleic
Acids presents an up-to-date and comprehensive account of the
structures and physical chemistry properties of nucleic acids,
with special emphasis on biological function. With a targeted
audience of 1)molecular biologists, 2)physical biochemists, and
3)physical chemists, the book has been carefully organized to
reach three different audiences while requiring only introductory
physical chemistry and molecular biology as prerequisites. Nucleic
Acids will serve as a textbook in physical biochemistry and
biophysical chemistry classes, as well as a supplemental text in
courses on nucleic acid biochemistry or molecular biology, and as
a personal reference for students and researchers in these
fields.


Key
Features




Organized
according to a systematic consideration of techniques
used in the study of nucleic acid structure and
properties.
Key
topics--such as protein-DNA and protein-drug complexes,
conformational transitions, characterization of nucleic
acids by gel and solution techniques, and behavior of
supercoiled DNA--are covered in great detail as veritable
mini-monographs.
Heavily
illustrated with diagrams, graphs, and molecular
structures, including nearly 2 dozen color figures.
Includes
numerous figures, tables and an extensive bibliography
to facilitate use as a reference volume.