This pocket-sized handbook is intended for medical students and beginning house officers. Its focus is to provide a succinct problem-based format for identifying disease processes, working up a differential diagnosis, employing the appropriate treatment, and anticipating the clinical course of the illness. The list of covered topics was generated based on the 100 most common pediatric admission and outpatient diagnoses at the top-ranked University of Washington's Children's Hospital and Medical Center. The book uses hot keys, mnemonics, tables and figures to help readers remember important facts. The authors are teaching residents at the University of Washington, and have used this material successfully in the training of medical students at their institution.