Committee on the Evaluation of 1950s Air Force Human Health Testing in Alaska Using Radioactive Iodine-131; Commission on Geosci National Academies Press (1996) Pehmeäkantinen kirja
National Research Council; Commission on Geosciences, Environment, and Resources; Ocean Studies Board; Committee on the Evaluati National Academies Press (2001) Pehmeäkantinen kirja
National Research Council; Division on Earth and Life Studies; Ocean Studies Board; Committee on the Evaluation of the Drakes Ba National Academies Press (2012) Pehmeäkantinen kirja
National Research Council; Policy and Global Affairs; Board on Higher Education and Workforce; Committee on the Evaluation of th National Academies Press (2004) Pehmeäkantinen kirja
Committee on the Ryan White CARE Act: Data for Resource Allocation; Planning and Evaluation; Board on Health Promotion and Disea National Academies Press (2004) Pehmeäkantinen kirja
Institute of Medicine; Committee on the Evaluation of the Department of Defense Comprehensive Clinical Evaluation Program National Academies Press (1997) Pehmeäkantinen kirja
Institute of Medicine; Committee on the Evaluation of the Department of Defense Comprehensive Clinical Evaluation Program National Academies Press (1997) Pehmeäkantinen kirja
Institute of Medicine; Committee on the Evaluation of the Department of Veterans Affairs Uniform Case Assessment Protocol National Academies Press (1998) Pehmeäkantinen kirja
Committee on an Evaluation of the US Department of Agriculture National Research Initiative Competitive Grants Program; Board on National Academies Press (2000) Pehmeäkantinen kirja
National Research Council; Division On Earth And Life Studies; Ocean Studies Board; Committee on the Evaluation of the Sea Grant National Academies Press (2006) Pehmeäkantinen kirja
Institute of Medicine; Food and Nutrition Board; Standing Committee on the Scientific Evaluation of Dietary Reference Intakes National Academies Press (2005) Kovakantinen kirja
Institute of Medicine; Food and Nutrition Board; Standing Committee on the Scientific Evaluation of Dietary Reference Intakes National Academies Press (2005) Pehmeäkantinen kirja
National Research Council; Division of Behavioral and Social Sciences and Education; Committee on the Independent Evaluation of National Academies Press (2011) Pehmeäkantinen kirja
Institute of Medicine; Food and Nutrition Board; Standing Committee on the Scientific Evaluation of Dietary Reference Intakes National Academies Press (1999) Pehmeäkantinen kirja
Committee on Review and Evaluation of the Army Non-Stockpile Chemical Material Disposal Program; Board on Army Science and Techn National Academies Press (1999) Pehmeäkantinen kirja
Institute of Medicine; Food and Nutrition Board; Standing Committee on the Scientific Evaluation of Dietary Reference Intakes National Academies Press (2000) Kovakantinen kirja
Committee on Review and Evaluation of the Army Non-Stockpile Chemical Material Disposal Program; Board on Army Science and Techn National Academies Press (2001) Pehmeäkantinen kirja
Institute of Medicine; Food and Nutrition Board; Standing Committee on the Scientific Evaluation of Dietary Reference Intakes National Academies Press (2002) Kovakantinen kirja
Institute of Medicine; Food and Nutrition Board; Standing Committee on the Scientific Evaluation of Dietary Reference Intakes National Academies Press (2001) Kovakantinen kirja
Committee on Review and Evaluation of the Army Non-Stockpile Chemical Material Disposal Program; Board on Army Science and Techn National Academies Press (2002) Pehmeäkantinen kirja
During the 1950s, with the Cold War looming, military planners sought to know more about how to keep fighting forces fit and capable in the harsh Alaskan environment. In 1956 and 1957, the U.S. Air Force's former Arctic Aeromedical Laboratory conducted a study of the role of the thyroid in human acclimatization to cold. To measure thyroid function under various conditions, the researchers administered a radioactive medical trace, Iodine-131, to Alaska Natives and white military personnel; based on the study results, the researchers determined that the thyroid did not play a significant role in human acclimatization to cold.
When this study of thyroid function was revisited at a 1993 conference on the Cold War legacy in the Arctic, serious questions were raised about the appropriateness of the activity—whether it posed risks to the people involved and whether the research had been conducted within the bounds of accepted guidelines for research using human participants. In particular, there was concern over the relatively large proportion of Alaska Natives used as subjects and whether they understood the nature of the study. This book evaluates the research in detail, looking at both the possible health effects of Iodine-131 administration in humans and the ethics of human subjects research. This book presents conclusions and recommendations and is a significant addition to the nation's current reevaluation of human radiation experiments conducted during the Cold War.
Table of Contents
Front Matter Executive Summary 1 Introduction 2 Health Effect of I131 Administration in Humans 3 The Ethics of Human Subjects Research 4 Conclusions and Recommendations 5 References A. Thyroid Function in Health and Disease B. Summary of the Public Session C. Thyroid Radaition Dose Estimates for I131 D. Secretary of Defense Letter E. Informed Consent Elements of Disclosure F. Principles for the Conduct of Research in the Arctic G. Biographical Sketches of Committee Members H. Glossary
