National Research Council; Division on Earth and Life Studies; Board on Environmental Studies and Toxicology; Committee on Fluor National Academies Press (2007) Pehmeäkantinen kirja
Subcommittee on Exposure Guidance Levels for Selected Hydrofluorocarbons; Committee on Toxicology; Board on Environmental Studie National Academies Press (2000) Pehmeäkantinen kirja
Most people associate fluoride with the practice of intentionally adding fluoride to public drinking water supplies for the prevention of tooth decay. However, fluoride can also enter public water systems from natural sources, including runoff from the weathering of fluoride-containing rocks and soils and leaching from soil into groundwater. Fluoride pollution from various industrial emissions can also contaminate water supplies. In a few areas of the United States fluoride concentrations in water are much higher than normal, mostly from natural sources. Fluoride is one of the drinking water contaminants regulated by the U.S. Environmental Protection Agency (EPA) because it can occur at these toxic levels. In 1986, the EPA established a maximum allowable concentration for fluoride in drinking water of 4 milligrams per liter, a guideline designed to prevent the public from being exposed to harmful levels of fluoride. Fluoride in Drinking Water reviews research on various health effects from exposure to fluoride, including studies conducted in the last 10 years.Table of Contents
Front matter Summary 1 Introduction 2 Measures of Exposure to Fluoride in the United States 3 Pharmacokinetics of Fluoride 4 Effects of Fluoride on Teeth 5 Musculoskeletal Effects 6 Reproductive and Developmental Effects of Fluoride 7 Neurotoxicity and Neurobehavioral Effects 8 Effects on the Endocrine System 9 Effects on the Gastrointestinal, Renal, Hepatic, and Immune Systems 10 Genotoxicity and Carcinogenicity 11 Drinking Water Standards for Fluoride References Appendix A Biographical Information on the Committee on Fluoride in Drinking Water Appendix B Measures of Exposure to Fluoride in the United States: Supplementary Information Appendix C Ecologic and Partially Ecologic Studies in Epidemiology Appendix D Comparative Pharmacokinetics of Rats and Humans Appendix E Detailed Information on Endocrine Studies of Fluoride