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Christopher I. Amos | Akateeminen Kirjakauppa

FORWARD-TIME POPULATION GENETICS SIMULATIONS - METHODS, IMPLEMENTATION, AND APPLICATIONS

Forward-Time Population Genetics Simulations - Methods, Implementation, and Applications
Bo Peng; Marek Kimmel; Christopher I. Amos
John Wiley and Sons Ltd (2012)
Pehmeäkantinen kirja
120,20
Tuotetta lisätty
ostoskoriin kpl
Siirry koriin
Forward-Time Population Genetics Simulations - Methods, Implementation, and Applications
120,20 €
John Wiley and Sons Ltd
Sivumäärä: 256 sivua
Asu: Pehmeäkantinen kirja
Julkaisuvuosi: 2012, 02.03.2012 (lisätietoa)
Kieli: Englanti
The only book available in the area of forward-time population genetics simulations—applicable to both biomedical and evolutionary studies The rapid increase of the power of personal computers has led to the use of serious forward-time simulation programs in genetic studies. Forward-Time Population Genetics Simulations presents both new and commonly used methods, and introduces simuPOP, a powerful and flexible new program that can be used to simulate arbitrary evolutionary processes with unique features like customized chromosome types, arbitrary nonrandom mating schemes, virtual subpopulations, information fields, and Python operators.

The book begins with an overview of important concepts and models, then goes on to show how simuPOP can simulate a number of standard population genetics models—with the goal of demonstrating the impact of genetic factors such as mutation, selection, and recombination on standard Wright-Fisher models. The rest of the book is devoted to applications of forward-time simulations in various research topics.

Forward-Time Population Genetics Simulations includes:



An overview of currently available forward-time simulation methods, their advantages, and shortcomings


An overview and evaluation of currently available software


A simuPOP tutorial


Applications in population genetics


Applications in genetic epidemiology, statistical genetics, and mapping complex human diseases



The only book of its kind in the field today, Forward-Time Population Genetics Simulations will appeal to researchers and students of population and statistical genetics.

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Forward-Time Population Genetics Simulations - Methods, Implementation, and Applicationszoom
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ISBN:
9780470503485
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