The volume, starting from the celebrated and fascinating Portrait of a Lady from the Poldi Pezzoli museum in Milan, one of the greatest masterpieces of Florentine portraiture from the latter half of the 15th century, investigates the art of the Pollaiolo brothers: Antonio, a goldsmith, painter and sculptor, and the most famous of the three; Piero, a painter; and Silvestro, who died young and was soon forgotten. Based on in- depth scientific analyses and research conducted on the methods of execution and materials used for the wide range of different works issued from the Pollaiolo brothers’ workshop, the volume presents paintings, drawings, engravings, sculptures, bronzes, and objects of applied art.