Principles of Scientific Writing and Biomedical Publication is a practical, comprehensive, state-of-the-art guide designed to enhance understanding of the principles of scientific publication, promote improved writing and manuscript preparation skills, and help navigate the seemingly complex pathway from manuscript submission, through peer review and revision, to successful publication. The book presents common issues that arise during the scientific publishing process; describes the ethical and practical aspects related to manuscript preparation, reporting research, and writing reviews and opinion articles; and guides authors on effectively interacting with journal editors. The unique feature of this book is that all contributors currently serve or have served as editors for major biomedical journals, including JAMA and the JAMA Network Journals, or have extensive experience and knowledge related to biomedical publications and information dissemination. Collectively, the authors of the 41 chapters in this book have published thousands of articles, including research reports and opinion articles, and have hundreds of "editor-years" of experience serving as editors of major journals. The authors also have been extensively involved with numerous aspects of biomedical publishing, including developing and implementing editorial policies and procedures; organizing and participating in international and national conferences and committees on peer review, scientific publishing, reporting guidelines, and biomedical information dissemination; and teaching scientific writing and publishing at academic centers and major conferences. Accordingly, the information, recommendations, and advice in this book are based on the collective insights of experienced editors and other experts in biomedical publication and will help guide the preparation of high-quality manuscripts suitable for publication in biomedical journals and demystify the scientific publication process.