In this issue of Obstetrics and Gynecology Clinics of North America, guest editor Dr. Sharon T. Phelan brings her considerable expertise to the topic of Prenatal Care. Prenatal care can help prevent complications and inform women about important steps they can take to protect their infant and ensure a healthy pregnancy. This issue not only provides timely updates but also touches on current issues in this fast-changing field, including social determinants of health care, health care disparities, and advocacy for the underserved pregnant patient.