Contemporary descriptions of who humans are and what belongs to their humanity are diverse and always changing, according to what various groups or individuals imagine them to be. Against this plurality, treatments on anthropology demonstrate a longing for clarity that is able to set right confusions and error. Theological Anthropology and Sin, volume 5 of the Confessional Lutheran Dogmatics series, allows Scripture and theology to speak to this question, yielding a permanent and essential portrayal of the human’s nature and structure, identity, sex, and personhood—constants that can stand against the whims of human imagination and the spirit of the age. The image of God, sin’s pervasiveness in each person’s life and in society, individuals’ relationship with their Creator, the tragedy of its corruption, and the ethical responsibility of humans are considered from a comprehensive evangelical Lutheran perspective, pointing the way forward for current and future generations of pastors, theologians, teachers, students of theology, and laypeople. Klaus Detlev Schulz is professor of pastoral ministry and missions and director of international studies at Concordia Theological Seminary in Ft. Wayne, Indiana.