This volume in honour of Karel Van Lerberghe contains 47 contributions by his colleagues and students dealing with the history and archaeology of the Syro-Mesopotamian area. The focus on Syria and on the Old-Babylonian period reflects Karel's main research interests. Quite some cuneiform tablets are published here for the first time (both in hand-copy and with the help of the Portable Light Dome). Most recent archaeological field research is presented in contributions concerning Ugarit, Tell Tweini, Tell Beydar and many other sites.