Tekijä: Mark D. Rothmann; Brian L. Wiens; Ivan S.F. Chan Kustantaja: Taylor & Francis Inc (2011) Saatavuus: | Arvioimme, että tuote lähetetään meiltä noin 1-3 viikossa
Tekijä: S.N. Sivanandam; S. Sumathi; S. N. Deepa Kustantaja: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG (2006) Saatavuus: Noin 17-20 arkipäivää
Tekijä: Alexey V. Borisov; Valery V. Kozlov; Ivan S. Mamaev; Mikhail A. Sokolovskiy Kustantaja: Springer-Verlag New York Inc. (2007) Saatavuus: Noin 17-20 arkipäivää
Tekijä: Alexey V. Borisov (ed.); Valery V. Kozlov (ed.); Ivan S. Mamaev (ed.); Mikhail A. Sokolovskiy (ed.) Kustantaja: Springer (2010) Saatavuus: Noin 17-20 arkipäivää
Tekijä: S.N. Sivanandam; S. Sumathi; S. N. Deepa Kustantaja: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG (2010) Saatavuus: Noin 17-20 arkipäivää
Tekijä: Macdonald; Ivan S; McLean; Robert Craik; Reed; Frederick; Keith; Fraser Sanderson; Toutloff; M. B Kustantaja: Kniga po trebovaniyu Saatavuus: | Arvioimme, että tuote lähetetään meiltä noin 1-3 viikossa
Taylor & Francis Inc Sivumäärä: 454 sivua Asu: Kovakantinen kirja Painos: 1 Julkaisuvuosi: 2011, 12.07.2011 (lisätietoa) Kieli: Englanti
The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Using examples from real clinical trials, Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the issues involved in the design of a non-inferiority trial. Each chapter begins with a non-technical introduction, making the text easily understood by those without prior knowledge of this type of trial.
Topics covered include:
A variety of issues of non-inferiority trials, including multiple comparisons, missing data, analysis population, the use of safety margins, the internal consistency of non-inferiority inference, the use of surrogate endpoints, trial monitoring, and equivalence trials Specific issues and analysis methods when the data are binary, continuous, and time-to-event The history of non-inferiority trials and the design and conduct considerations for a non-inferiority trial The strength of evidence of an efficacy finding and how to evaluate the effect size of an active control therapy
A comprehensive discussion on the purpose and issues involved with non-inferiority trials, Design and Analysis of Non-inferiority Trials will assist current and future scientists and statisticians on the optimal design of non-inferiority trials and in assessing the quality of non-inferiority comparisons done in practice.
