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Concepts and Models for Drug Permeability Studies - Cell and Tissue based In Vitro Culture Models
Bruno Sarmento; Catarina Leite Pereira; José Das Neves
Elsevier - Health Sciences Division (2024)
Kovakantinen kirja
204,50
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Basic Income Experiments : A Critical Examination of Their Goals, Contexts, and Methods
Roberto Merrill; Catarina Neves; Bru Laín
Palgrave Macmillan (2022)
Pehmeäkantinen kirja
107,50
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Concepts and Models for Drug Permeability Studies - Cell and Tissue based In Vitro Culture Models
204,50 €
Elsevier - Health Sciences Division
Sivumäärä: 706 sivua
Asu: Kovakantinen kirja
Painos: 2. ed.
Julkaisuvuosi: 2024, 23.02.2024 (lisätietoa)
Kieli: Englanti
Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models, Second Edition, summarizes the most important developments in in vitro models for predicting the permeability of drugs. This book is structured around three different approaches, summarizing the most recent achievements regarding models comprising (i) immortalized cells with an intrinsic ability to grow as monolayers when seeded in permeable supports, (ii) primary cells isolated from living organisms and directly cultured as barrier monolayers, and (iii) tissue-based models constructed with cell lines and extracellular matrix that resembles the tridimensional structure of mucosae and other biological membranes, or animal/patient-derived tissues. Each model is covered in detail, including the protocol of generation and application for specific drugs/drug delivery systems. The equivalence between in vitro cell and tissue models and in vivo conditions is discussed, highlighting how each model may provisionally resemble different drug absorption route. Chapters included in the first edition were updated with relevant data published in recent years, while four new chapters were included to reflect new emerging directions and trends in drug permeability models.

Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models, Second Edition, is a critical reference for drug discovery and drug formulation scientists interested in delivery systems intended for the administration of drugs through mucosal routes and other important tissue barriers (e.g. the BBB). Researchers studying mucosal biology can use this book to familiarize themselves and exploit the synergic effect of mucosal delivery systems and biomolecules.

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Tilaustuote | Arvioimme, että tuote lähetetään meiltä noin 1-3 viikossa. | Tilaa jouluksi viimeistään 27.11.2024. Tuote ei välttämättä ehdi jouluksi.
Myymäläsaatavuus
Helsinki
Tapiola
Turku
Tampere
Concepts and Models for Drug Permeability Studies - Cell and Tissue based In Vitro Culture Modelszoom
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ISBN:
9780443155109
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