The traditional concept of the doctor-patient relationship born in the days of family physicians has undergone drastic changes because of the dramatic advancement in medical technology, availability of sophisticated imaging system, high tech electronics, and preponderance of new diseases. With the immense strides in technology, health care has emerged as a profitable sector attracting investors from varied backgrounds. Seeing the vast privatization of health sector, the Government and Ministry of Health enforced certain rules, regulations, and Acts for this sector. The purpose of this manual is to educate medical practitioners about the rules, regulations, Acts, and legal procedures that are required to start their practices.